How much have you heard about Centrophenoxine? I guess very little. It is perhaps least mentioned or referred to acetylcholine supplement in the market. However, Centrophenoxine is one among the most effective nootropic supplements you can ever use. 50 years of research has proved that this compound is a cognitive enhancer, a powerful neuroprotectant, and a cholinergic compound.

What is Centrophenoxine?

Centrophenoxine is a cholinergic compound with Dimethylaminoethanol (DMAE) component. In the United States, this acetylcholine supplement is sold under the brand name Lucidril. The good news is that you can purchase it from online stores or over-the-counter as might be convenient to you. We can define DMAE as a choline molecule featuring one less methyl group. DMAE is one of the few compounds that can inhibit the accumulation of the age pigmentation referred to as beta-amyloid.

Centrophenoxine is a synthetic, specially modified version of DMAE designed to optimize absorption and increase transportation across the blood-brain barrier. In other words, this drug is an altered version of DMAE that is capable of reaching your brain easily and quickly. It is usually grouped together with other acetylcholine supplements because it also increases the activities of this neurotransmitter.

Benefits of Centrophenoxine

The researchers that developed Centrophenoxine wanted a drug they could use to reverse the neurologic effects of aging. However, further research has demonstrated that it has many more effects in cognitive enhancement and other nootropic effects.

Centrophenoxine can reduce and eliminate lipofuscin, which is which accumulates on aging skin cells leading to skin spots. It also reduces age-related accumulation of potassium in brain cells, which makes it extremely difficult for your brain cells to communicate with each other leading to cognitive decline. It flushes all these wastes to make nerves and other brain cells communicate with each other and improve efficiency and overall health of your brain.

If you take the right dose of Centrophenoxine, you can enjoy all the benefits of DMAE including improved memory, better thinking, better focus, alertness, learning, better attention and healthier mood.


Centrophenoxine Dosage

The recommended daily dosage for Centrophenoxine is between 500mg and 1000mg. However, the dosage is dependent on why you are using the supplement. If you are using it as an anti-aging agent, you may require higher doses. However, it would be wise to speak to a medical expert before you use this supplement as an anti-aging drug. You also need to consult with your doctor if you are using it for the first time.

This supplement increases brain energy, and the effects last for several hours. This means you must consider taking it in early hours. If you take it in the afternoon, chances are that you will not be able to sleep at night due to increased brain activity.

A good way to unlock all the nootropic benefits of this acetylcholine supplement is to use it in combination with other nootropic agents, especially those belonging to Racetam family. Although experts will normally advise you to start at lower doses, the story is different if you are using it in a stack. You can start at the higher dosage, at least at the beginning.

Centrophenoxine is safe and well tolerated but some side effects are common especially at high doses. The side effects to be aware of include nausea, headaches, dizziness, irritability, gastrointestinal disturbances and mild insomnia. Reduce the dosage to recommended levels if you notice any of these side effects. And remember to consult with your doctor before taking any medication.


J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 758–. ISBN 978-1-4757-2085-3.

The Science of Anti-aging Medicine. American Academy of Anti-Aging Med. 1 January 2003. pp. 66–. ISBN 978-0-9668937-3-1.