What do you know about Choline Bitartrate? I guess not much and clearly, you would like to know more. In case you have considered using an acetylcholine supplement to boost your mental and physical performance, then this is vital for you to consider all the available options.

What is Choline Bitartrate?

Choline Bitartrate is a brain supplement that helps people to improve their memory and mental performance. This supplement is a direct precursor of the acetylcholine neurotransmitter. Acetylcholine is one of the most powerful neurotransmitters and it works in your brain to control memory formation and mental performance. Raising the levels of acetylcholine in your brain is the reason why you need Choline Bitartrate supplement.

Choline Bitartrate is not a controlled product meaning you can buy it over-the-counter. It comes in the form of tablets, capsules, and powder to choose from.The supplement combines choline with Bitartrate salt. The salt makes it easy for your body to absorb the choline.

How to Use Choline Bitartrate

According to experts and seasonal users of this supplement, you will achieve better results by combining it in a stack with more powerful cholinergic supplements such as Piracetam or Aniracetam. However, this supplement is a low choline content compared to Alpha GPC Choline and CDP Choline. Therefore, it may not provide you with the same level of cognitive abilities as those powerful cholinergic supplements.

A good way of unlocking the full benefits of Choline Bitartrate is to ensure you take it alongside the diets high in choline. A few benefits you can expect include protection against memory loss associated with aging, better focus, and alertness. However, you can go for more potent acetylcholine supplements if you want something that will give you a greater intellectual edge.

How Does It Work?

Remember Choline Bitartrate is taken orally. Once in your intestines, it is absorbed into your bloodstream. As the blood flows through your system, it reaches your brain and the substance has to cross the blood-brain barrier. This barrier is highly selective and prevents many substances from entering, so your body converts Choline Bitartrate into a form that is capable of crossing your brain barrier with ease.

Not all the Choline Bitartrate you consume therefore reaches your brain. For this reason, it is less efficient compared to Choline such as Alpha GPC, Centrophenoxine, or Citicoline (CDP Choline). FDA recommends a daily dosage of choline at 550 mg for men and 425 mg for women each day.

Possible Side Effects

Generally, Choline Bitartrate is a safe and well-tolerated acetylcholine supplement. Rare side effects may happen at high doses. Possible side effects may include gastrointestinal disturbances (vomiting, diarrhea, and stomachache), some dizziness, increased salivation and perspiration, low blood pressure and fishy body odor.


“Choline”. Micronutrient Information Center, Linus Pauling Institute, Oregon State University, Corvallis, Oregon. February 2015. Retrieved 10 January 2017.

Zeisel, SH (1981). “Dietary choline: biochemistry, physiology, and pharmacology.”. Annual review of nutrition1: 95–121. PMID 6764726.