Galantamine goes with many other brand names including Lycoremine, Nivalin, Reminyl, Razadyne and Razadyne ER. It is possible you have heard about it as one of the treatments for mild to moderate Alzheimer’s disease. Did you know that Galantamine is also a powerful acetylcholine supplement that you can use to optimize your cognitive performance?
You can find this nootropic supplement in a prescription form as well as an over-the-counter supplement in one-day extended release capsule, twice-a-day tablets and in an oral solution (liquid). The Galantamine supplements are available in 8mg, 16mg, and 24mg pills. When used to treat mild to moderate cases of Alzheimer’s-related dementia and cognitive decline, Galantamine improves memory, abstract thinking, judgment, and lucid dreaming.
Galantamine and Lucid Dreaming
How Does Galantamine Work?
This acetylcholine supplement works by inhibiting the actions of acetylcholinesterase. You may refer to it as an acetylcholinesterase inhibitor. Acetylcholinesterase is an enzyme present in your brain at the sites where transmission of electric nerve impulses between neurons takes place (synapse or neural junctions). It destroys acetylcholine after it does its work of neurotransmission.
Galantamine inhibits these actions thereby increasing the concentration of acetylcholine at the synapse. With a high concentration of acetylcholine in your brain, you will enjoy all the cognitive enhancing benefits of the neurotransmitter. The inhibition is reversible. What does this mean to you? It means the effects of Galantamine will fade after some time lowering the risks of severe side effects.
You should always consult with your doctor before taking Galantamine, even though it is the over-the-counter drug, because taking excessive doses may lead to serious negative side effects. Normally, experts will recommend galantamine dosages of between 16mg and 24mg per day. This means you can take one extended-release galantamine 24mg capsule or take 2 or 3 8mg tablets daily.
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Precautions To Using Galantamine
You should not use this supplement if you are allergic to ingredients used in its formulation. You should also avoid galantamine if you have severe kidney and liver problems. This is why it is important for you to consult your doctor or healthcare provider before buying and using Galantamine.
Some drugs may also interact negatively with Galantamine. For example, Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (may increase the risk of bowel and stomach bleeding), cholinergic agents such as bethanechol, cholinesterase inhibitors such as donepezil, selective serotonin reuptake inhibitors (SSRIs) such as paroxetine and ketoconazole. The combination of these drugs may cause serious side effects.
Be extra careful when using anticholinergics such as scopolamine since galantamine may decrease the effectiveness of this drug. Use it cautiously with an elder member of your family because he or she may be more sensitive to its effects. Efficacy and safety of galantamine have not been demonstrated on children and so you should not give it to them.
Possible Side Effects
Galantamine is a powerful cognitive enhancer that is safe to use and well tolerated at the recommended doses. If you take higher doses, you risk experiencing a number of side effects, some of which are very severe. Mild side effects may include drowsiness, dizziness, fainting, nausea, vomiting, and diarrhea. In rare cases, you may develop a severe form of skin reaction known as Stevens-Johnson syndrome/toxic epidermal necrolysis.
Giunta B, Ehrhart J, Townsend K et al. Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120. Brain Res Bull 2004; 64: 165–70.
Mashkovsky, MD; Kruglikova–Lvova, RP (1951). “On the pharmacology of the new alkaloid galantamine”. Farmakologia Toxicologia. 14: 27–30.
“Safety Alerts for Human Medical Products > Reminyl (galantamine hydrobromide)”. # MedWatch The FDA Safety Information and Adverse Event Reporting Program.